Okres Krupina, located in the southern part of Banská Bystrica Region, was established in 1996, inheriting a history deeply intertwined with the medieval Kingdom of Hungary and later Czechoslovakia.

Geographically, Krupina district is characterized by a diverse landscape encompassing the Štiavnica Mountains, Krupinská planina plateau, and the southern slopes of the Javorie mountain range, contributing to its agricultural potential and natural beauty.

The district's population is predominantly Slovak, with a noticeable Roma minority, reflecting broader demographic trends in Slovakia and creating a multicultural environment.

Historically, Krupina was an important medieval mining town, although its mineral wealth never reached the scale of nearby Banská Štiavnica, leaving agriculture as a more consistent economic driver.

The region's economy is largely based on agriculture, particularly fruit growing and viticulture, taking advantage of the favorable climatic conditions in the south of Slovakia.

Krupina is known for its traditional folk architecture, which can still be observed in some villages, showcasing the region's rich cultural heritage through its well-preserved rural buildings.

The Modrý Kameň Castle, overlooking the town of Modrý Kameň, is a significant landmark in the Krupina district, showcasing medieval architecture and hosting a museum dedicated to puppet theater culture.

Krupina was granted town privileges in 1238 by King Béla IV, highlighting its early importance as a trading and administrative center in the region.

While not a UNESCO World Heritage site itself, the district borders the Banská Štiavnica and Technical Monuments in its Vicinity UNESCO site, impacting tourism and regional development initiatives.

The district's involvement in various historical events, including the Turkish Wars and the Slovak National Uprising, demonstrates its significance in the broader context of Slovak and Central European history.

Krupina experiences a moderate continental climate, characterized by warm summers and cold winters, significantly influencing the types of crops that can be cultivated in the region.

The population of the Krupina district has generally been declining in recent decades, mainly due to emigration to larger urban centers and lower birth rates, presenting demographic challenges.

The annual Krupina Fair, a traditional folk festival, attracts visitors from across the region, showcasing local crafts, culinary traditions, and providing a platform for social interaction.

Although no major scientific breakthroughs originated directly from Krupina, the district has contributed to agricultural research and development, particularly in the areas of fruit growing and wine production.

Local traditions such as folk music, dance, and crafts are still actively practiced in Krupina and its surrounding villages, preserved by cultural organizations and passed down through generations, contributing to the unique identity of the region.