Otofuke is situated in the central-eastern part of Hokkaido, within the fertile Tokachi Plain, and is traversed by the Otofuke River, a significant tributary of the larger Tokachi River.

The town officially began its administrative history in 1900 with the establishment of the Otofuke village office, founded by settlers primarily from Honshu who sought to cultivate its abundant land.

The name "Otofuke" is derived from the Ainu language word "O-to-puke," which is widely interpreted to mean "river of soil" or "river with earth falling," describing the characteristics of the local Otofuke River.

Agriculture forms the cornerstone of Otofuke's economy, renowned for its expansive fields that produce a diverse array of crops including wheat, potatoes, sugar beets, and various vegetables, making it a key food supplier for Japan.

As of recent years, Otofuke maintains a relatively stable population of around 44,000 residents, defying the shrinking trend seen in some rural areas due to its robust economic foundation and quality of life.

Otofuke is notably home to Tokachigawa Onsen, one of Hokkaido's rare "Moor Onsen," famed for its unique plant-derived, reddish-brown water rich in natural humic substances that provide excellent moisturizing properties.

The town hosts the vibrant Otofuke Yosakoi Soran Festival annually, an energetic event showcasing spirited dance performances that draw numerous participants and spectators from across the Tokachi region.

Following World War II, Otofuke experienced significant agricultural expansion and modernization, playing a crucial role in Japan's post-war food supply through the adoption of advanced farming techniques.

Beyond crop cultivation, dairy farming constitutes another major industry in Otofuke, with numerous dairy farms contributing substantially to Hokkaido's status as Japan's leading milk and dairy product producer.

Tokachi Hills is a popular agricultural theme park and botanical garden in Otofuke, offering visitors beautifully curated flower gardens, farm-to-table dining experiences, and opportunities to purchase local produce.

The town is well-connected by national routes 241 and 274, facilitating the efficient transport of its agricultural products to markets and enhancing accessibility for residents and tourists alike.

Otofuke is celebrated for its local culinary specialties, particularly dishes that highlight its high-quality potatoes and wheat, which can be savored in local restaurants and roadside stations throughout the area.

The town actively promotes sustainable agriculture and environmental conservation, leveraging its rich natural resources responsibly to ensure long-term ecological health and economic viability.

Given its prominence in agriculture, Otofuke frequently collaborates with leading agricultural research institutions within Hokkaido to develop innovative crop varieties and advanced farming technologies.

Otofuke plays a crucial role as a central agricultural hub within the broader Tokachi region, significantly contributing to Hokkaido's overall economic output and Japan's national food self-sufficiency efforts.